Package: mr.raps 0.4.3

Qingyuan Zhao

mr.raps: Two Sample Mendelian Randomization using Robust Adjusted Profile Score

Mendelian randomization is a method of identifying and estimating a confounded causal effect using genetic instrumental variables. This packages implements methods for two-sample Mendelian randomization with summary statistics by using Robust Adjusted Profile Score (RAPS). References: Qingyuan Zhao, Jingshu Wang, Gibran Hemani, Jack Bowden, Dylan S. Small. Statistical inference in two-sample summary-data Mendelian randomization using robust adjusted profile score. <arxiv:1801.09652>; Qingyuan Zhao, Yang Chen, Jingshu Wang, Dylan S. Small. Powerful genome-wide design and robust statistical inference in two-sample summary-data Mendelian randomization. <arxiv:1804.07371>.

Authors:Qingyuan Zhao [aut, cre], Jingshu Wang [aut]

mr.raps_0.4.3.tar.gz
mr.raps_0.4.3.zip(r-4.7)mr.raps_0.4.3.zip(r-4.6)mr.raps_0.4.3.zip(r-4.5)
mr.raps_0.4.3.tgz(r-4.6-any)mr.raps_0.4.3.tgz(r-4.5-any)
mr.raps_0.4.3.tar.gz(r-4.7-any)mr.raps_0.4.3.tar.gz(r-4.6-any)
mr.raps_0.4.3.tgz(r-4.6-emscripten)
manual.pdf |manual.html
card.svg |card.png
mr.raps/json (API)
NEWS

# Install 'mr.raps' in R:
install.packages('mr.raps', repos = c('https://remlapmot.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/qingyuanzhao/mr.raps/issues

Datasets:
  • bmi.ais - Effect of Body Mass Index
  • bmi.bmi - "Effect" of Body Mass Index
  • bmi.cad - Effect of Body Mass Index
  • bmi.sbp - Effect of Body Mass Index
  • cad.bmi - Effect of Coronary Artery Disease
  • cad.cad - Effect of Coronary Artery Disease
  • crp.cad - Effect of C-Reactive Protein on Coronary Artery Disease
  • lipid.cad - Effect of blood lipids (LDL cholesterol, HDL cholesterol, Triglycerides) on Cardiovascular disease risk

On CRAN:

Conda:

5.37 score 42 stars 1 packages 185 scripts 57 downloads 12 exports 23 dependencies

Last updated from:dd79b5bd74. Checks:9 OK. Indexed: no.

TargetResultTimeFilesSyslog
linux-devel-x86_64OK213
source / vignettesOK251
linux-release-x86_64OK221
macos-release-arm64OK137
macos-oldrel-arm64OK148
windows-develOK182
windows-releaseOK186
windows-oldrelOK167
wasm-releaseOK175

Exports:fit.mixture.modelmodal.plotmr.rapsmr.raps.mlemr.raps.mle.allmr.raps.overdispersedmr.raps.overdispersed.robustmr.raps.scatterplotmr.raps.shrinkagemr.raps.simplemr.raps.simple.robustposterior.mean

Dependencies:clicpp11farverggplot2ggrepelgluegridExtragtableisobandlabelinglifecyclenortestR6RColorBrewerRcpprlangrootSolversnpsS7scalesvctrsviridisLitewithr